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Dermal Fibroblasts from the Red Duroc Pig Have an Inherently Fibrogenic Phenotype: An in vitro Model of Fibroproliferative Scarring

BACKGROUND: The pathophysiology of hypertrophic scarring is unknown due in part to the lack of a robust animal model. Although the red Duroc pig has emerged as a promising in vivo model, the cellular mechanisms underlying Duroc scarring are unknown, and the size and cost of Duroc pigs are obstacles...

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Detalhes bibliográficos
Publicado no:Plast Reconstr Surg
Main Authors: Sood, Ravi F., Muffley, Lara A., Seaton, Max E., Ga, Maricar, Sirimahachaiyakul, Pornthep, Hocking, Anne M., Gibran, Nicole S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624253/
https://ncbi.nlm.nih.gov/pubmed/26505702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0000000000001704
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