Dlk1-Mediated Temporal Regulation of Notch Signaling Is Required for Differentiation of Alveolar Type II to Type I Cells during Repair

Lung alveolar type I cells (AT1) and alveolar type II cells (AT2) regulate the structural integrity and function of alveoli. AT1, covering ~95% of the surface area, are responsible for gas exchange, whereas AT2 serve multiple functions, including alveolar repair through proliferation and differentia...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Finn, Johanna, Sottoriva, Kilian, Pajcini, Kostandin V., Kitajewski, Jan K., Chen, Chang, Zhang, Wei, Malik, Asrar B., Liu, Yuru
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464111/
https://ncbi.nlm.nih.gov/pubmed/30865885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.02.046
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