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Loss of growth hormone–mediated signal transducer and activator of transcription 5 (STAT5) signaling in mice results in insulin sensitivity with obesity
Growth hormone (GH) has an important function as an insulin antagonist with elevated insulin sensitivity evident in humans and mice lacking a functional GH receptor (GHR). We sought the molecular basis for this sensitivity by utilizing a panel of mice possessing specific deletions of GHR signaling p...
में बचाया:
में प्रकाशित: | FASEB J |
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मुख्य लेखकों: | , , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Federation of American Societies for Experimental Biology
2019
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6463913/ https://ncbi.nlm.nih.gov/pubmed/30779881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802328R |
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