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Loss of growth hormone–mediated signal transducer and activator of transcription 5 (STAT5) signaling in mice results in insulin sensitivity with obesity

Growth hormone (GH) has an important function as an insulin antagonist with elevated insulin sensitivity evident in humans and mice lacking a functional GH receptor (GHR). We sought the molecular basis for this sensitivity by utilizing a panel of mice possessing specific deletions of GHR signaling p...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:FASEB J
मुख्य लेखकों: Chhabra, Yash, Nelson, Caroline N., Plescher, Monika, Barclay, Johanna L., Smith, Aaron G., Andrikopoulos, Sof, Mangiafico, Salvatore, Waxman, David J., Brooks, Andrew J., Waters, Michael J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Federation of American Societies for Experimental Biology 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463913/
https://ncbi.nlm.nih.gov/pubmed/30779881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802328R
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