Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G(0)/G(1) switch gene 2 (G0S2)

G(0)/G(1) switch gene 2 (G0S2) is a specific inhibitor of adipose triglyceride lipase (ATGL), the rate-limiting enzyme for intracellular lipolysis. Recent studies show that G0S2 plays a critical role in promoting triacylglycerol (TG) accumulation in the liver, and its encoding gene is a direct targe...

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Bibliographic Details
Published in:FASEB J
Main Authors: Zhang, Xiaodong, Xie, Xitao, Heckmann, Bradlee L., Saarinen, Alicia M., Gu, Haiwei, Zechner, Rudolf, Liu, Jun
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2019
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463910/
https://ncbi.nlm.nih.gov/pubmed/30802154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802502R
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