Regulation of G0/G1 Switch Gene 2 (G0S2) Protein Ubiquitination and Stability by Triglyceride Accumulation and ATGL Interaction

Intracellular triglyceride (TG) hydrolysis or lipolysis is catalyzed by the key intracellular triglyceride hydrolase, adipose triglyceride lipase (ATGL). The G0/G1 Switch Gene 2 (G0S2) was recently identified as the major selective inhibitor of ATGL and its hydrolase function. Since G0S2 levels are...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Heckmann, Bradlee L., Zhang, Xiaodong, Saarinen, Alicia M., Liu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889065/
https://ncbi.nlm.nih.gov/pubmed/27248498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156742
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