Structure and Function of Tryptophan–Tyrosine Dyads in Biomimetic β Hairpins

[Image: see text] Tyrosine–tryptophan (YW) dyads are ubiquitous structural motifs in enzymes and play roles in proton-coupled electron transfer (PCET) and, possibly, protection from oxidative stress. Here, we describe the function of YW dyads in de novo designed 18-mer, β hairpins. In Peptide M, a Y...

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Julkaisussa:J Phys Chem B
Päätekijät: McCaslin, Tyler G., Pagba, Cynthia V., Chi, San-Hui, Hwang, Hyea J., Gumbart, James C., Perry, Joseph W., Olivieri, Cristina, Porcelli, Fernando, Veglia, Gianluigi, Guo, Zhanjun, McDaniel, Miranda, Barry, Bridgette A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2019
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463897/
https://ncbi.nlm.nih.gov/pubmed/30888824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b12452
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