Cyclins B1, T1, and H differ in their molecular mode of interaction with cytomegalovirus protein kinase pUL97

Human cytomegalovirus (HCMV) is a common β-herpesvirus causing life-long latent infections. HCMV replication interferes with cell cycle regulation in host cells because the HCMV-encoded cyclin-dependent kinase (CDK) ortholog pUL97 extensively phosphorylates the checkpoint regulator retinoblastoma pr...

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Gardado en:
Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Steingruber, Mirjam, Keller, Lena, Socher, Eileen, Ferre, Sabrina, Hesse, Anne-Marie, Couté, Yohann, Hahn, Friedrich, Büscher, Nicole, Plachter, Bodo, Sticht, Heinrich, Marschall, Manfred
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463711/
https://ncbi.nlm.nih.gov/pubmed/30782840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007049
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