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Cyclins B1, T1, and H differ in their molecular mode of interaction with cytomegalovirus protein kinase pUL97

Human cytomegalovirus (HCMV) is a common β-herpesvirus causing life-long latent infections. HCMV replication interferes with cell cycle regulation in host cells because the HCMV-encoded cyclin-dependent kinase (CDK) ortholog pUL97 extensively phosphorylates the checkpoint regulator retinoblastoma pr...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Steingruber, Mirjam, Keller, Lena, Socher, Eileen, Ferre, Sabrina, Hesse, Anne-Marie, Couté, Yohann, Hahn, Friedrich, Büscher, Nicole, Plachter, Bodo, Sticht, Heinrich, Marschall, Manfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463711/
https://ncbi.nlm.nih.gov/pubmed/30782840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007049
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