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Structural basis of the target-binding mode of the G protein–coupled receptor kinase–interacting protein in the regulation of focal adhesion dynamics

Focal adhesions (FAs) are specialized sites where intracellular cytoskeleton elements connect to the extracellular matrix and thereby control cell motility. FA assembly depends on various scaffold proteins, including the G protein–coupled receptor kinase-interacting protein 1 (GIT1), paxillin, and l...

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Vydáno v:J Biol Chem
Hlavní autoři: Liang, Mingfu, Xie, Xingqiao, Pan, Jian, Jin, Gaowei, Yu, Cong, Wei, Zhiyi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463692/
https://ncbi.nlm.nih.gov/pubmed/30737283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006915
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