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Structural insights into ankyrin repeat–mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion

Kidney ankyrin repeat–containing proteins (KANK1/2/3/4) belong to a family of scaffold proteins, playing critical roles in cytoskeleton organization, cell polarity, and migration. Mutations in KANK proteins are implicated in cancers and genetic diseases, such as nephrotic syndrome. KANK proteins can...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Pan, Wenfei, Sun, Kang, Tang, Kun, Xiao, Qingpin, Ma, Chenxue, Yu, Cong, Wei, Zhiyi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808758/
https://ncbi.nlm.nih.gov/pubmed/29217769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815779
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