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Structural insights into ankyrin repeat–mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion

Kidney ankyrin repeat–containing proteins (KANK1/2/3/4) belong to a family of scaffold proteins, playing critical roles in cytoskeleton organization, cell polarity, and migration. Mutations in KANK proteins are implicated in cancers and genetic diseases, such as nephrotic syndrome. KANK proteins can...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Pan, Wenfei, Sun, Kang, Tang, Kun, Xiao, Qingpin, Ma, Chenxue, Yu, Cong, Wei, Zhiyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808758/
https://ncbi.nlm.nih.gov/pubmed/29217769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815779
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