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Inflammation-mediated fetal injury by maternal granulocyte-colony stimulating factor and high-dose intraamniotic endotoxin in the caprine model

OBJECTIVE: To define a novel experimental model with maternal intravenous (i.v.) granulocyte-colony stimulating factor (G-CSF) followed by a single- and high-dose of 20 mg intra-amniotic (IA) endotoxin to induce fetal brain injury in the preterm fetal goat. MATERIALS AND METHODS: Pregnant goats (n=4...

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Publicado en:Turk J Obstet Gynecol
Main Authors: Sezik, Mekin, Köker, Afşin, Özmen, Özlem, Halıgür, Mehmet, Kaşıkçı, Duygu, Aydoğan, Ahmet, Özatik, Orhan
Formato: Artigo
Idioma:Inglês
Publicado: Galenos Publishing 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463425/
https://ncbi.nlm.nih.gov/pubmed/31019839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjod.tjod.galenos.2019.92300
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