KRAS mutations in the parental tumour accelerate in vitro growth of tumoroids established from colorectal adenocarcinoma

The aim of the present study was to characterize a patient‐derived in vitro 3D model (ie tumoroid) established from colorectal adenocarcinoma. This study investigated the growth rate of tumoroids and whether the Kirsten rat sarcoma (KRAS) mutations in the parental tumour accelerate this rate. The tu...

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Veröffentlicht in:Int J Exp Pathol
Hauptverfasser: Mousavi, Nabi, Truelsen, Sarah Line Bring, Hagel, Grith, Jorgensen, Lars Nannestad, Harling, Henrik, Timmermans, Vera, Melchior, Linea Cecilie, Thysen, Anna Hammerich, Heegaard, Steffen, Thastrup, Jacob
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463397/
https://ncbi.nlm.nih.gov/pubmed/30884019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12308
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