KRAS mutations in the parental tumour accelerate in vitro growth of tumoroids established from colorectal adenocarcinoma

The aim of the present study was to characterize a patient‐derived in vitro 3D model (ie tumoroid) established from colorectal adenocarcinoma. This study investigated the growth rate of tumoroids and whether the Kirsten rat sarcoma (KRAS) mutations in the parental tumour accelerate this rate. The tu...

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Detalhes bibliográficos
Publicado no:Int J Exp Pathol
Main Authors: Mousavi, Nabi, Truelsen, Sarah Line Bring, Hagel, Grith, Jorgensen, Lars Nannestad, Harling, Henrik, Timmermans, Vera, Melchior, Linea Cecilie, Thysen, Anna Hammerich, Heegaard, Steffen, Thastrup, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463397/
https://ncbi.nlm.nih.gov/pubmed/30884019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12308
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