Spinal glial cell line-derived neurotrophic factor infusion reverses reduction of Kv4.1-mediated A-type potassium currents of injured myelinated primary afferent neurons in a neuropathic pain model

High frequency spontaneous activity in injured primary afferents has been proposed as a pathological mechanism of neuropathic pain following nerve injury. Although spinal infusion of glial cell line-derived neurotrophic factor reduces the activity of injured myelinated A-fiber neurons after fifth lu...

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Bibliographic Details
Published in:Mol Pain
Main Authors: Shinoda, Masamichi, Fukuoka, Tetsuo, Takeda, Mamoru, Iwata, Koichi, Noguchi, Koichi
Format: Artigo
Language:Inglês
Published: SAGE Publications 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463340/
https://ncbi.nlm.nih.gov/pubmed/30868936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806919841196
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