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Phosphatidylinositol 4,5‐bisphosphate controls Rab7 and PLEKMH1 membrane cycling during autophagosome–lysosome fusion
The small GTPase Rab7 is a key organizer of receptor sorting and lysosomal degradation by recruiting of a variety of effectors depending on its GDP/GTP‐bound state. However, molecular mechanisms that trigger Rab7 inactivation remain elusive. Here we find that, among the endosomal pools, Rab7‐positiv...
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| Udgivet i: | EMBO J |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6463214/ https://ncbi.nlm.nih.gov/pubmed/31368593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100312 |
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