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Mutation-Based Therapeutic Strategies for Duchenne Muscular Dystrophy: From Genetic Diagnosis to Therapy

Duchenne and Becker muscular dystrophy (DMD/BMD) are X-linked muscle disorders caused by mutations of the DMD gene, which encodes the subsarcolemmal protein dystrophin. In DMD, dystrophin is not expressed due to a disruption in the reading frame of the DMD gene, resulting in a severe phenotype. Beck...

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Detalhes bibliográficos
Publicado no:J Pers Med
Autor principal: Nakamura, Akinori
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462977/
https://ncbi.nlm.nih.gov/pubmed/30836656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm9010016
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