The copper-sensing transcription factor Mac1, the histone deacetylase Hst1, and nicotinic acid regulate de novo NAD(+) biosynthesis in budding yeast

NADH (NAD(+)) is an essential metabolite involved in various cellular biochemical processes. The regulation of NAD(+) metabolism is incompletely understood. Here, using budding yeast (Saccharomyces cerevisiae), we established an NAD(+) intermediate–specific genetic system to identify factors that re...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: James Theoga Raj, Christol, Croft, Trevor, Venkatakrishnan, Padmaja, Groth, Benjamin, Dhugga, Gagandeep, Cater, Timothy, Lin, Su-Ju
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462523/
https://ncbi.nlm.nih.gov/pubmed/30760525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006987
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