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Thiamine Biosynthesis in Saccharomyces cerevisiae Is Regulated by the NAD(+)-Dependent Histone Deacetylase Hst1

Genes encoding thiamine biosynthesis enzymes in microorganisms are tightly regulated such that low environmental thiamine concentrations activate transcription and high concentrations are repressive. We have determined that multiple thiamine (THI) genes in Saccharomyces cerevisiae are also regulated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Mingguang, Petteys, Brian J., McClure, Julie M., Valsakumar, Veena, Bekiranov, Stefan, Frank, Elizabeth L., Smith, Jeffrey S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897578/
https://ncbi.nlm.nih.gov/pubmed/20439498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01590-09
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