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Thiamine Biosynthesis in Saccharomyces cerevisiae Is Regulated by the NAD(+)-Dependent Histone Deacetylase Hst1

Genes encoding thiamine biosynthesis enzymes in microorganisms are tightly regulated such that low environmental thiamine concentrations activate transcription and high concentrations are repressive. We have determined that multiple thiamine (THI) genes in Saccharomyces cerevisiae are also regulated...

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Main Authors: Li, Mingguang, Petteys, Brian J., McClure, Julie M., Valsakumar, Veena, Bekiranov, Stefan, Frank, Elizabeth L., Smith, Jeffrey S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897578/
https://ncbi.nlm.nih.gov/pubmed/20439498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01590-09
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