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Thiamine Biosynthesis in Saccharomyces cerevisiae Is Regulated by the NAD(+)-Dependent Histone Deacetylase Hst1

Genes encoding thiamine biosynthesis enzymes in microorganisms are tightly regulated such that low environmental thiamine concentrations activate transcription and high concentrations are repressive. We have determined that multiple thiamine (THI) genes in Saccharomyces cerevisiae are also regulated...

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Detalhes bibliográficos
Main Authors: Li, Mingguang, Petteys, Brian J., McClure, Julie M., Valsakumar, Veena, Bekiranov, Stefan, Frank, Elizabeth L., Smith, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897578/
https://ncbi.nlm.nih.gov/pubmed/20439498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01590-09
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