Enhanced Antitumor Immune Response in 2′-5′ Oligoadenylate Synthetase-Like 1- (OASL1-) Deficient Mice upon Cisplatin Chemotherapy and Radiotherapy

Type I interferon (IFN-I) plays a critical role in the antitumor immune response. In our previous study, we showed that IFN-I-inducible 2′-5′ oligoadenylate synthetase-like 1 (OASL1) negatively regulated IFN-I production upon tumor challenge similar to that of viral infection. Thus, OASL1-deficient...

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Dettagli Bibliografici
Pubblicato in:J Immunol Res
Autori principali: Sim, Chan Kyu, Lee, Jung Hoon, Baek, In-Jeoung, Lee, Sang-Wook, Lee, Myeong Sup
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462330/
https://ncbi.nlm.nih.gov/pubmed/31049360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7596786
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