Enhanced Antitumor Immune Response in 2′-5′ Oligoadenylate Synthetase-Like 1- (OASL1-) Deficient Mice upon Cisplatin Chemotherapy and Radiotherapy

Type I interferon (IFN-I) plays a critical role in the antitumor immune response. In our previous study, we showed that IFN-I-inducible 2′-5′ oligoadenylate synthetase-like 1 (OASL1) negatively regulated IFN-I production upon tumor challenge similar to that of viral infection. Thus, OASL1-deficient...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Sim, Chan Kyu, Lee, Jung Hoon, Baek, In-Jeoung, Lee, Sang-Wook, Lee, Myeong Sup
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462330/
https://ncbi.nlm.nih.gov/pubmed/31049360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7596786
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