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Hydroalcoholic Extract of Levisticum officinale Increases cGMP Signaling Pathway by Down-Regulating PDE5 Expression and Induction of Apoptosis in MCF-7 and MDA-MB-468 Breast Cancer Cell Lines

BACKGROUND: This study aimed to investigate Levisticum officinale hydroalcoholic extract (LOHE) effect on both cGMP signaling pathway and phosphodiesterase 5 (PDE5) gene expression pattern and to examine the role of LOHE in apoptosis induction of MCF-7 and MDA-MB-468 cell lines. METHODS: The half ma...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Iran Biomed J
Prif Awduron: Sargazi, Marzieh Lotfian, Saravani, Ramin, Shahraki, Ali
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Pasteur Institute 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462291/
https://ncbi.nlm.nih.gov/pubmed/30388886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29252/.23.4.280
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