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Inhibition of Phosphodiesterase 5 and Increasing the Level of Cyclic Guanosine 3′,5′ Monophosphate by Hydroalcoholic Achillea wilhelmsii C. Koch Extract in Human Breast Cancer Cell Lines MCF-7 and MDA-Mb-468

This study aimed to investigate the effect of hydroalcoholic Achillea wilhelmsii C. Koch extract (HAWE) on phosphodiesterase 5 (PDE5) gene expression and cyclic guanosine 3′,5′ monophosphate (cGMP) signaling in the MCF-7 and MDA-Mb-468 cell lines. The effective dose (ED50) of HAWE was examined in bo...

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Publicat a:Breast Cancer (Auckl)
Autors principals: Saravani, Ramin, Galavi, Hamid Reza, Shahraki, Ali
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391053/
https://ncbi.nlm.nih.gov/pubmed/28469435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1178223417690178
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