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LRP1 deficiency in microglia blocks neuro-inflammation in the spinal dorsal horn and neuropathic pain processing

Following injury to the peripheral nervous system (PNS), microglia in the spinal dorsal horn (SDH) become activated and contribute to the development of local neuro-inflammation, which may regulate neuropathic pain processing. The molecular mechanisms that control microglial activation and its effec...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Brifault, Coralie, Kwon, HyoJun, Campana, Wendy M., Gonias, Steven L
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462253/
https://ncbi.nlm.nih.gov/pubmed/30746765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23599
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