Tauroursodeoxycholic acid (TUDCA) abolishes chronic high salt-induced renal injury and inflammation

AIM: Chronic high salt intake exaggerates renal injury and inflammation, especially with the loss of functional ET(B) receptors. Tauroursodeoxycholic acid (TUDCA) is a chemical chaperone and bile salt that is approved for the treatment of hepatic diseases. Our aim was to determine whether TUDCA is r...

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Vydáno v:Acta Physiol (Oxf)
Hlavní autoři: De Miguel, C., Sedaka, R., Kasztan, M., Lever, J. M., Sonnenberger, M., Abad, A., Jin, C., Carmines, P. K., Pollock, D. M., Pollock, J. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462246/
https://ncbi.nlm.nih.gov/pubmed/30501003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.13227
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