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VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine

Patients with major depressive disorder (MDD) often have structural and functional deficits in the ventromedial prefrontal cortex (vmPFC), but the underlying molecular pathways are incompletely understood. The neuropeptide precursor VGF (non-acronymic) plays a critical role in depression and antidep...

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Publicat a:Neuropsychopharmacology
Autors principals: Jiang, Cheng, Lin, Wei-Jye, Labonté, Benoit, Tamminga, Carol A., Turecki, Gustavo, Nestler, Eric J., Russo, Scott J., Salton, Stephen R.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462025/
https://ncbi.nlm.nih.gov/pubmed/30504797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0277-4
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