VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine

Patients with major depressive disorder (MDD) often have structural and functional deficits in the ventromedial prefrontal cortex (vmPFC), but the underlying molecular pathways are incompletely understood. The neuropeptide precursor VGF (non-acronymic) plays a critical role in depression and antidep...

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Publicado no:Neuropsychopharmacology
Main Authors: Jiang, Cheng, Lin, Wei-Jye, Labonté, Benoit, Tamminga, Carol A., Turecki, Gustavo, Nestler, Eric J., Russo, Scott J., Salton, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462025/
https://ncbi.nlm.nih.gov/pubmed/30504797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0277-4
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