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Ganoderma lucidum extract ameliorates MPTP-induced parkinsonism and protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis

Neuroprotection targeting mitochondrial dysfunction has been proposed as an important therapeutic strategy for Parkinson’s disease. Ganoderma lucidum (GL) has emerged as a novel agent that protects neurons from oxidative stress. However, the detailed mechanisms underlying GL-induced neuroprotection...

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Dettagli Bibliografici
Pubblicato in:Acta Pharmacol Sin
Autori principali: Ren, Zhi-li, Wang, Chao-dong, Wang, Tao, Ding, Hui, Zhou, Ming, Yang, Nan, Liu, Yan-yong, Chan, Piu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461997/
https://ncbi.nlm.nih.gov/pubmed/29991712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0077-8
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