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Ganoderma lucidum extract ameliorates MPTP-induced parkinsonism and protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis

Neuroprotection targeting mitochondrial dysfunction has been proposed as an important therapeutic strategy for Parkinson’s disease. Ganoderma lucidum (GL) has emerged as a novel agent that protects neurons from oxidative stress. However, the detailed mechanisms underlying GL-induced neuroprotection...

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Bibliografiske detaljer
Udgivet i:Acta Pharmacol Sin
Main Authors: Ren, Zhi-li, Wang, Chao-dong, Wang, Tao, Ding, Hui, Zhou, Ming, Yang, Nan, Liu, Yan-yong, Chan, Piu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461997/
https://ncbi.nlm.nih.gov/pubmed/29991712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0077-8
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