Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids

The re-emergence of Zika virus (ZIKV) in the Western Hemisphere has resulted in global public health crisis since 2015. ZIKV preferentially infects and targets human neural progenitor cells (hNPCs) and causes fetal microcephaly upon maternal infection. hNPCs not only play critical roles during fetal...

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Gepubliceerd in:Cell Res
Hoofdauteurs: Xu, Yan-Peng, Qiu, Yang, Zhang, Boya, Chen, Guilai, Chen, Qi, Wang, Miao, Mo, Fan, Xu, Jiuyue, Wu, Jin, Zhang, Rong-Rong, Cheng, Meng-Li, Zhang, Na-Na, Lyu, Bao, Zhu, Wen-Liang, Wu, Meng-Hua, Ye, Qing, Zhang, Da, Man, Jiang-Hong, Li, Xiao-Feng, Cui, Jie, Xu, Zhiheng, Hu, Baoyang, Zhou, Xi, Qin, Cheng-Feng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461993/
https://ncbi.nlm.nih.gov/pubmed/30814679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0152-9
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