Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids

The re-emergence of Zika virus (ZIKV) in the Western Hemisphere has resulted in global public health crisis since 2015. ZIKV preferentially infects and targets human neural progenitor cells (hNPCs) and causes fetal microcephaly upon maternal infection. hNPCs not only play critical roles during fetal...

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Publicado no:Cell Res
Main Authors: Xu, Yan-Peng, Qiu, Yang, Zhang, Boya, Chen, Guilai, Chen, Qi, Wang, Miao, Mo, Fan, Xu, Jiuyue, Wu, Jin, Zhang, Rong-Rong, Cheng, Meng-Li, Zhang, Na-Na, Lyu, Bao, Zhu, Wen-Liang, Wu, Meng-Hua, Ye, Qing, Zhang, Da, Man, Jiang-Hong, Li, Xiao-Feng, Cui, Jie, Xu, Zhiheng, Hu, Baoyang, Zhou, Xi, Qin, Cheng-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461993/
https://ncbi.nlm.nih.gov/pubmed/30814679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0152-9
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