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The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation

The expression of the long noncoding RNA HOTAIR (HOX Transcript Antisense Intergenic RNA) is largely deregulated in epithelial cancers and positively correlates with poor prognosis and progression of hepatocellular carcinoma and gastrointestinal cancers. Furthermore, functional studies revealed a pi...

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Bibliographic Details
Published in:Cell Death Differ
Main Authors: Battistelli, Cecilia, Sabarese, Giovanna, Santangelo, Laura, Montaldo, Claudia, Gonzalez, Frank J., Tripodi, Marco, Cicchini, Carla
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461983/
https://ncbi.nlm.nih.gov/pubmed/30154449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0170-z
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