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The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation

The expression of the long noncoding RNA HOTAIR (HOX Transcript Antisense Intergenic RNA) is largely deregulated in epithelial cancers and positively correlates with poor prognosis and progression of hepatocellular carcinoma and gastrointestinal cancers. Furthermore, functional studies revealed a pi...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Battistelli, Cecilia, Sabarese, Giovanna, Santangelo, Laura, Montaldo, Claudia, Gonzalez, Frank J., Tripodi, Marco, Cicchini, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461983/
https://ncbi.nlm.nih.gov/pubmed/30154449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0170-z
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