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SYNTHESIS OF 2′-O-PHOTOCAGED RIBONUCLEOSIDE PHOSPHORAMIDITES

The chemical synthesis and incorporation of the phosphoramidite derivatives of 2′-O-photocaged ribonucleosides (A, C, G and U) with o-nitrobenzyl, α-methyl-o-nitrobenzyl or 4,5-dimethoxy-2-nitrobenzyl group into oligoribonucleotides are described. The efficiency of UV irradiated uncaging of these 2′...

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Publicat a:Nucleosides Nucleotides Nucleic Acids
Autors principals: Lu, Jun, Koo, Selene C., Li, Nan-Sheng, Piccirilli, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461471/
https://ncbi.nlm.nih.gov/pubmed/25621705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770.2014.965256
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