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Functional instability allows access to DNA in longer transcription Activator-Like effector (TALE) arrays
Transcription activator-like effectors (TALEs) bind DNA through an array of tandem 34-residue repeats. How TALE repeat domains wrap around DNA, often extending more than 1.5 helical turns, without using external energy is not well understood. Here, we examine the kinetics of DNA binding of TALE arra...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6461438/ https://ncbi.nlm.nih.gov/pubmed/30810525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38298 |
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