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Stochastic Processes and Component Placticity Governing DNA Mismatch Repair

DNA mismatch repair (MMR) is a DNA excision-resynthesis process that principally enhances replication fidelity. Highly conserved MutS (MSH) and MutL (MLH/PMS) homologs initiate MMR and in higher eukaryotes act as DNA damage sensors that can trigger apoptosis. MSH proteins recognize mismatched nucleo...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Liu, Jiaquan, Lee, Jong-Bong, Fishel, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461355/
https://ncbi.nlm.nih.gov/pubmed/29864444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.05.039
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