Molecular determinants of WNT9b responsiveness in nephron progenitor cells

Primed nephron progenitor cells (NPCs) appear in metanephric mesenchyme by E11.5 and differentiate in response to the inductive WNT9b signal from the ureteric bud. However, the NPC WNT-receptor complex is unknown. We obtained M15 cells from E10.5 mesonephric mesenchyme and systematically analyzed co...

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Udgivet i:PLoS One
Main Authors: Dickinson, Kyle K., Hammond, Leah C., Karner, Courtney M., Hastie, Nicholas D., Carroll, Thomas J., Goodyer, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461349/
https://ncbi.nlm.nih.gov/pubmed/30978219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215139
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