RNA as a key factor in driving or preventing self-assembly of the TAR DNA-binding protein 43

Amyotrophic lateral sclerosis and frontotemporal lobar degeneration are incurable motor neuron diseases associated with muscle weakness, paralysis and respiratory failure. Accumulation of TAR DNA-binding protein 43 (TDP-43) as toxic cytoplasmic inclusions is one of the hallmarks of these pathologies...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Zacco, Elsa, Graña-Montes, Ricardo, Martin, Stephen R., de Groot, Natalia Sanchez, Alfano, Caterina, Tartaglia, Gian Gaetano, Pastore, Annalisa
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461199/
https://ncbi.nlm.nih.gov/pubmed/30742796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.01.028
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados