Endothelial cells secreted endothelin-1 augments diabetic nephropathy via inducing extracellular matrix accumulation of mesangial cells in ETBR(-/-) mice

Endothelin B receptor (ETBR) deficiency may contribute to the progression of diabetic nephropathy (DN) in a streptozotocin (STZ) model, but the underlying mechanism is not fully revealed. In this study, STZ-diabetic ETBR(-/-) mice was characterized by increased serum creatinine and urinary albumin,...

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Sparad:
Bibliografiska uppgifter
I publikationen:Aging (Albany NY)
Huvudupphovsmän: Zou, Hong-hong, Wang, Li, Zheng, Xiao-xu, Xu, Gao-si, Shen, Yunfeng
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals 2019
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461170/
https://ncbi.nlm.nih.gov/pubmed/30926764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101875
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