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Endothelial cells secreted endothelin-1 augments diabetic nephropathy via inducing extracellular matrix accumulation of mesangial cells in ETBR(-/-) mice
Endothelin B receptor (ETBR) deficiency may contribute to the progression of diabetic nephropathy (DN) in a streptozotocin (STZ) model, but the underlying mechanism is not fully revealed. In this study, STZ-diabetic ETBR(-/-) mice was characterized by increased serum creatinine and urinary albumin,...
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| Publicado en: | Aging (Albany NY) |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Impact Journals
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6461170/ https://ncbi.nlm.nih.gov/pubmed/30926764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101875 |
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