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RNA Interference-Based Cancer Drugs: The Roadblocks, and the “Delivery” of the Promise

Nucleic acid-based therapeutics like synthetic small interfering RNAs have been exploited to modulate gene function, taking advantage of RNA interference (RNAi), an evolutionally conserved biological process. Recently, the world's first RNAi drug was approved for a rare genetic disorder in the...

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Detalhes bibliográficos
Publicado no:Nucleic Acid Ther
Main Authors: Das, Manisit, Musetti, Sara, Huang, Leaf
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461149/
https://ncbi.nlm.nih.gov/pubmed/30562145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2018.0762
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