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Silica nanoparticles trigger the vascular endothelial dysfunction and prethrombotic state via miR-451 directly regulating the IL6R signaling pathway

BACKGROUND: Safety evaluation is a prerequisite for nanomaterials in a wide range of fields, including chemical industries, medicine or food sciences. Previously, we had demonstrated that SiNPs could trigger the thrombotic effects in vivo, but the underlying mechanisms remain unknown. This study was...

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Détails bibliographiques
Publié dans:Part Fibre Toxicol
Auteurs principaux: Feng, Lin, Yang, Xiaozhe, Liang, Shuang, Xu, Qing, Miller, Mark R., Duan, Junchao, Sun, Zhiwei
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460825/
https://ncbi.nlm.nih.gov/pubmed/30975181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-019-0300-x
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