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Silica nanoparticles trigger the vascular endothelial dysfunction and prethrombotic state via miR-451 directly regulating the IL6R signaling pathway

BACKGROUND: Safety evaluation is a prerequisite for nanomaterials in a wide range of fields, including chemical industries, medicine or food sciences. Previously, we had demonstrated that SiNPs could trigger the thrombotic effects in vivo, but the underlying mechanisms remain unknown. This study was...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Feng, Lin, Yang, Xiaozhe, Liang, Shuang, Xu, Qing, Miller, Mark R., Duan, Junchao, Sun, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460825/
https://ncbi.nlm.nih.gov/pubmed/30975181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-019-0300-x
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