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Tailoring Corynebacterium glutamicum towards increased malonyl-CoA availability for efficient synthesis of the plant pentaketide noreugenin

BACKGROUND: In the last years, different biotechnologically relevant microorganisms have been engineered for the synthesis of plant polyphenols such as flavonoids and stilbenes. However, low intracellular availability of malonyl-CoA as essential precursor for most plant polyphenols of interest is re...

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Pubblicato in:Microb Cell Fact
Autori principali: Milke, Lars, Kallscheuer, Nicolai, Kappelmann, Jannick, Marienhagen, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460773/
https://ncbi.nlm.nih.gov/pubmed/30975146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1117-x
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