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Engineering intracellular malonyl-CoA availability in microbial hosts and its impact on polyketide and fatty acid synthesis
Malonyl-CoA is an important central metabolite serving as the basic building block for the microbial synthesis of many pharmaceutically interesting polyketides, but also fatty acid–derived compounds including biofuels. Especially Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutam...
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| Publicado no: | Appl Microbiol Biotechnol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7316851/ https://ncbi.nlm.nih.gov/pubmed/32385515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-020-10643-7 |
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