Skewed X-inactivation is common in the general female population

X-inactivation is a well-established dosage compensation mechanism ensuring that X-chromosomal genes are expressed at comparable levels in males and females. Skewed X-inactivation is often explained by negative selection of one of the alleles. We demonstrate that imbalanced expression of the paterna...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Shvetsova, Ekaterina, Sofronova, Alina, Monajemi, Ramin, Gagalova, Kristina, Draisma, Harmen H. M., White, Stefan J., Santen, Gijs W. E., Chuva de Sousa Lopes, Susana M., Heijmans, Bastiaan T., van Meurs, Joyce, Jansen, Rick, Franke, Lude, Kiełbasa, Szymon M., den Dunnen, Johan T., ‘t Hoen, Peter A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460563/
https://ncbi.nlm.nih.gov/pubmed/30552425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-018-0291-3
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