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Transcriptional Autoregulatory Loops Are Highly Conserved in Vertebrate Evolution

BACKGROUND: Feedback loops are the simplest building blocks of transcriptional regulatory networks and therefore their behavior in the course of evolution is of prime interest. METHODOLOGY: We address the question of enrichment of the number of autoregulatory feedback loops in higher organisms. Firs...

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Autors principals: Kiełbasa, Szymon M., Vingron, Martin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527657/
https://ncbi.nlm.nih.gov/pubmed/18791639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003210
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