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Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth
Excessive signaling through gp130, the shared receptor for the interleukin (IL)6 family of cytokines, is a common hallmark in solid malignancies and promotes their progression. Here, we established the in vivo utility of bazedoxifene, a steroid analog clinically approved for the treatment of osteopo...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | EMBO Mol Med |
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Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
John Wiley and Sons Inc.
2019
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6460354/ https://ncbi.nlm.nih.gov/pubmed/30885958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809539 |
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