Impaired cellular energy metabolism in cord blood macrophages contributes to abortive response toward inflammatory threats

Neonatal sepsis is characterized by hyperinflammation causing enhanced morbidity and mortality compared to adults. This suggests differences in the response towards invading threats. Here we investigate activated cord blood macrophages (CBMΦ) in comparison to adult macrophages (PBMΦ), indicating inc...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Dreschers, Stephan, Ohl, Kim, Lehrke, Michael, Möllmann, Julia, Denecke, Bernd, Costa, Ivan, Vogl, Thomas, Viemann, Dorothee, Roth, Johannes, Orlikowsky, Thorsten, Tenbrock, Klaus
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459909/
https://ncbi.nlm.nih.gov/pubmed/30976008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09359-8
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