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Diverse small molecules prevent macrophage lysis during pyroptosis
Pyroptosis is a programmed process of proinflammatory cell death mediated by caspase-1-related proteases that cleave the pore-forming protein, gasdermin D, causing cell lysis and release of inflammatory intracellular contents. The amino acid glycine prevents pyroptotic lysis via unknown mechanisms,...
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| Published in: | Cell Death Dis |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6459844/ https://ncbi.nlm.nih.gov/pubmed/30975978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1559-4 |
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