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Development of an Indirect Competitive ELISA for Glycocholic Acid Based on Chicken Single-Chain Variable Fragment (scFv) Antibodies

Glycocholic acid (GCA) is an important metabolite of bile acids, whose urine levels are expected to be a specific diagnostic biomarker for hepatocellular carcinoma (HCC). A high-throughput immunoassay for determination of GCA would be of significant advantage and useful for primary diagnosis, survei...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Cui, Xiping, Vasylieva, Natalia, Wu, Panpan, Barnych, Bogdan, Yang, Jun, Shen, Ding, He, Qiyi, Gee, Shirley J., Zhao, Suqing, Hammock, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459402/
https://ncbi.nlm.nih.gov/pubmed/28942640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b03190
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