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Necroptotic Cell Death Promotes Adaptive Immunity Against Colonizing Pneumococci

Pore-forming toxin (PFT) induced necroptosis exacerbates pulmonary injury during bacterial pneumonia. However, its role during asymptomatic nasopharyngeal colonization and toward the development of protective immunity was unknown. Using a mouse model of Streptococcus pneumoniae (Spn) asymptomatic co...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Riegler, Ashleigh Nichole, Brissac, Terry, Gonzalez-Juarbe, Norberto, Orihuela, Carlos J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459137/
https://ncbi.nlm.nih.gov/pubmed/31019504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00615
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